A pair of working-class brothers flee their Reno Motel after getting involved in a fatal hit-and-run accident.

Moronic American student Rusty arranges a student exchange program for his closest friend and him to study in Romania for six months and meet his Internet girlfriend Draguta. He travels with potheads Pete and Wang; Pete's girlfriend Lia and his twin sister Danni; the naive and romantic Newmar and his dippy girlfriend Lynne; the nerd Brady and crook Cliff. His friends actually intend to party. While traveling by train to Razvan, they learn that five hundred years ago, vampire Radu lost his beloved Stephania, whose spirit was trapped in a music box. Radu has kept Stephania's body and has been seeking the music box to bring Stephania back. Meanwhile, one of Radu's minions retrieves the music box but is mortally wounded by the vampire slayer Teodora Van Sloan and he drops the object in a gypsy's basket. Newmar buys the music box and gives it to Lynne. When they arrive at the university...

After her mother, Karen (Melissa Leo) gets married for the third time, 17-year-old Greta (Hillary Duff), who had witnessed her father kill himself, withdraws within herself, and turns rebellious. In lieu of boot camp she is sent to live with her maternal grandparents, Katherine (Ellen Burstyn) and Joseph (Michael Murphy) where she makes it known that she is determined to kill herself. She then falls for a cook, Julie (Evan Ross) at the local restaurant, much to the chagrin of her grandparents - especially when they find out he had been interned in a juvenile correctional facility. Faced with all-round opposition and unhappy with her life Greta plans her suicide during a boating trip - a plan that will not only expose closeted skeletons, but also shatter and change everyone's lives forever.